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As selective serotonin reuptake inhibitors. Paxil works by helping to restore the balance of certain natural chemicals in the brain. Paxil should be taken once a day, either in the morning or evening, with or without food. Zoloft, Paxil, Luvox and Prozac are currently used by more than five million Americans. Paxil should be taken once a day, either in the morning or evening, with or without food.
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